Science & Technology

Research Leader – CADD

Not Specified

For 70 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.

*Job Summary*

No two days are ever the same in our fast-paced environment, and joining our CADD team in Saffron Walden, UK will see you provide scientific excellence to influence and impact upon drug discovery programs. In partnership with other senior scientific leaders, your extensive CADD experience will help to shape the future scientific strategy in CADD and medicinal chemistry. You will be a positive role model with a demonstrated ability to inspire and mentor the next generation of CADD scientists within Charles River.


CADD discipline leadership within multiple integrated projects, using expertise and skills to influence project direction and strategy

Project leadership of dedicated computational chemistry projects, delivering on objectives, managing resources, finances and client communication

To provide broader scientific leadership, mentoring others and helping to define future scientific direction

To identify and implement new technologies to enhance capabilities within CADD and medicinal chemistry

Act as CADD lead within business development activities, preparing proposals and presenting to prospective clients

Promote high scientific visibility of Discovery capabilities, both internally and externally

*Candidate Profile*

A first degree or equivalent in chemistry or a closely related subject

A PhD in a field of relevance to molecular modelling

Extensive CADD experience, with a minimum of 10 years within a drug discovery environment supporting projects across different phases of drug discovery

Excellent interpersonal, communication and presentation skills

A dynamic and flexible approach towards achieving client-based objectives, and demonstrable ability to deliver on multiple projects simultaneously and meet challenging deadlines

A strong track record of scientific leadership and exceptional problem solving skills that has impacted positively on the delivery of drug discovery projects

An active interest in new technologies, with a drive and passion to innovate and integrate them into common practice

Models the Charles River Values of Care, Lead, Own and Collaborate

About Discovery

Discovery from Charles River is industry-proven in the successful development of novel therapies, with over 350 patents and 80 preclinical drug candidates delivered to our sponsors in the past 17 years. Backed by more than 650 scientists, our comprehensive, integrated portfolio employs the latest technology and platforms to provide chemistry, biology, and pharmacology services that support clients from the earliest stages of hit identification all the way through to IND. Our client-focused, collaborative approach creates true partnerships that anticipate challenges, overcome obstacles, and move us forward together on the journey of getting new drugs to market.

About Charles River

Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.

With over 17,000 employees within 90 facilities in 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. And in 2019, revenue increased to $2.62 billion.

At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of ~85% of the drugs approved by the FDA in 2019.